Aminoglycoside resistance mechanism inference algorithm: Implication for underlying resistance mechanisms to aminoglycosides

Mechanisms Underlying Broad Spectrum Resistance

Mechanisms Underlying Broad Spectrum Resistance Genome-wide interactions between Xanthomonas oryzae pv. oryzae (Xoo) and rice resulting from a broad-spectrum hypersensitive reaction (BSHR) mediated by a new rice R gene, Xa39, were investigated by comparative dynamic transcriptomic profiles in the incompatible and compatible interactions using three related rice lines and a highly virulent Xoo i...

Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance.

Aminoglycosides: activity and resistance.

Aminoglycosides are highly potent, broad-spectrum antibiotics with many desirable properties for the treatment of lifethreatening infections (28). Their history begins in 1944 with streptomycin and was thereafter marked by the successive introduction of a series of milestone compounds (kanamycin, gentamicin, and tobramycin) which definitively established the usefulness of this class of antibiot...

Investigating the underlying mechanism of resistance to Ascaris infection.

The generative mechanism(s) of predisposition to Ascaris infection are currently unknown. While many factors play a role in interindividual infection intensity, much focus has been placed on the host's immunological response to infection and the underlying genetics. The present review describes the research conducted that has examined various immunological parameters and genetic factors that ma...

Multiple resistance to aminoglycoside antibiotics in actinomycetes.

Actinomycetes were characterized in terms of resistance to 11 different aminoglycoside antibiotics (AGs). Strains freshly isolated in AG containing media showed wide varieties of multiple AG resistance, while the majority of ISP (International Streptomyces Project) cultures and the actinomycete strains isolated in an AG free medium were susceptible to all or most of the AGs tested. Marked chara...